Publications
Anginera Angiogenesis Research
Kellar RS, Shepherd BR, Larson DF, Naughton G, Williams SK. Cardiac Patch Constructed from Human Fibroblasts Attenuates Reduction in Cardiac Function after Acute Infarct. Tissue Engineering 11 (11/12):1678-1687. 2005.
Roberts C, Ratcliffe A, Mansbridge J, Kellar RS. Tissue Engineering for Tissue and Organ Repair: Angiogenesis as a Mechanism of Action. Recent Research Developments in Biomaterials. 323-334. 2002.
Kellar RS, Landeen LK, Shepherd BR, Naughton GK, Ratcliffe A, Williams SK. Scaffold-Based, Three-Dimensional, Human Fibroblast Culture Provides a Structural Matrix That Supports Angiogenesis in Infarcted Heart Tissue. Circulation 2001; 104:2063-2068. 2001.
Thai, HM. Juneman, E, Castellano, L, Do, R, Hagerty, T, Lancaster, J, Kellar, RS, Williams, S, Sethis, G, Schmetz, M, Gaballa, M, and Goldman, S. Implantation of a 3 dimensional fibroblast matrix improves left ventricular function and blood flow after acute myocardial infarction. Cell Transplantation. Accepted for publication, (2008).
Dermagraft Studies
Gentzkow GD. Dermagraft: living bioengineered, human dermis for healing chronic wounds. In The Wound Management Manual, Bok Y. Lee, editor. McGraw-Hill, New York, 2005
Gentzkow, G, Jensen J, Pollak R, et al. Improved healing of diabetic foot ulcers after grafting with a living human dermal replacement. Wounds, 11(3):77-84, 1999
Pollak RA, Edington H, Jensen JL, Kroeker RO, Gentzkow GD. A human dermal replacement for the treatment of diabetic foot ulcers. Wounds, 9(6):175-183, 1997
Naughton G, Mansbridge J, Gentzkow G. A Metabolically Active Human Dermal Replacement for the Treatment of Diabetic Foot Ulcers. Artificial Organs, 21(11):1203-1210, 1997
Gentzkow GD, Iwasaki I, Hershon KS, et al. Use of Dermagraft, a Cultured Human Dermis, to Treat Diabetic Foot Ulcers. Diabetes Care, 19(4):350-354, 1996
Omar AA, Mavor AI, Jones AM, Homer-Vanniasinkam S. Treatment of venous leg ulcers with Dermagraft. Eur. J. Vasc Endovasc Surg., 2004 Jun;27(6):666-72.
Marston WA, Hanft J, Norwood P, Pollak R; Dermagraft Diabetic Foot Ulcer Study Group. The efficacy and safety of Dermagraft in improving the healing of chronic diabetic foot ulcers: results of a prospective randomized trial. Diabetes Care, 2003 Jun;26(6):1701-5.
Newton DJ, Khan F, Belch JJ, Mitchell MR, Leese GP. Blood flow changes in diabetic foot ulcers treated with dermal replacement therapy. J. Foot Ankle Surg., 2002 Jul-Aug;41(4):233-7.
Pinney E, Liu K, Sheeman B, Mansbridge J. Human three-dimensional fibroblast cultures express angiogenic activity. J Cell Physiol., 2000; 183(1):74-82.
Naughton GK, Mansbridge JN. Human-based tissue-engineered implants for plastic and reconstructive surgery. Clin Plast Surg. 1999 Oct;26(4):579-86, viii.
Mansbridge JN, Liu K, Pinney RE, Patch R, Ratcliffe A, Naughton GK. Growth factors secreted by fibroblasts: role in healing diabetic foot ulcers. Diabetes Obes Metab. 1999 Sep;1(5):265-79.
Mansbridge J, Liu K, Pinney E, Patch R, Ratcliffe A, Naughton G. Growth factors secreted by fibroblasts: role in healing diabetic foot ulcers. Diabetes, Obesity and Metabolism, 1999; 1:265-279.
Jiang WG, Harding KG. Enhancement of wound tissue expansion and angiogenesis by matrix-embedded fibroblast (dermagraft), a role of hepatocyte growth factor/scatter factor. Int J Mol Med, 1998; 2(2):203-210.